Cysteine-Rich Secretory Proteins (CRISPs) from Venomous Snakes: An Overview of the Functional Diversity in a Large and Underappreciated Superfamily
The CAP protein superfamily (Cysteine-rich secretory proteins (CRISPs), drosselklappe stellantrieb Antigen 5 (Ag5), and Pathogenesis-related 1 (PR-1) proteins) is widely distributed, but for toxinologists, snake venom CRISPs are the most familiar members.Although CRISPs are found in the majority of venoms, very few of these proteins have been funct